Cell Biology: A Tense but Good Day for Actin at Cell–Cell Junctions
نویسندگان
چکیده
Cells have evolved an elegant tuning mechanism to maintain tissue integrity, in which increasing mechanical tension stimulates actin assembly at cell-cell junctions. The mechanosensitive junctional protein α-catenin acts through vinculin and Ena/VASP proteins to reinforce the cell against mechanical stress.
منابع مشابه
Expression of Neurotrophins in Adipose-derived Stem Cells during in vitro Culture and Posttransplantation in Parkinsonian Rat Model
Background: Adipose tissue stem cells (ASCs) cause faster repair of damaged tissue posttransplantation by releasing growth factors in neurodegenerative diseases. ASCs secrete factors in the culture medium called conditioned medium (CM) in vitro. This study investigated the expression of neurotrophin genes in vitro culture and transplant of ASCs in Parkinsonian rats. Materials and Methods: In th...
متن کاملMycoremediation of Dichlorvos Pesticide Contaminated Soil by Pleurotus pulmonarius (Fries) Quelet
The extensive use of pesticides leads to accumulation of a huge amount of residues in the environment. As such, the present study investigates the potentiality of Pleurotus pulmonarius to bioremediate dichlorvos pesticides (2,2-dichlorovinyldimethylphosphate) in contaminated soil. DDVP-polluted soils have been contaminated in five concentrations (5% v/w, 10% v/w, 15% v/w, 20% v/w, and 25% v/w),...
متن کاملMycoremediation of Dichlorvos Pesticide Contaminated Soil by Pleurotus pulmonarius (Fries) Quelet
The extensive use of pesticides leads to accumulation of a huge amount of residues in the environment. As such, the present study investigates the potentiality of Pleurotus pulmonarius to bioremediate dichlorvos pesticides (2,2-dichlorovinyldimethylphosphate) in contaminated soil. DDVP-polluted soils have been contaminated in five concentrations (5% v/w, 10% v/w, 15% v/w, 20% v/w, and 25% v/w),...
متن کاملFormin-mediated actin polymerization at cell–cell junctions stabilizes E-cadherin and maintains monolayer integrity during wound repair
Cadherin-mediated cell-cell adhesion is required for epithelial tissue integrity in homeostasis, during development, and in tissue repair. E-cadherin stability depends on F-actin, but the mechanisms regulating actin polymerization at cell-cell junctions remain poorly understood. Here we investigated a role for formin-mediated actin polymerization at cell-cell junctions. We identify mDia1 and Fm...
متن کاملCytoplasmic actin in postsynaptic structures at the neuromuscular junction
We used an antibody prepared against Aplysia (mollusc) body-wall actin that specifically reacts with certain forms of cytoplasmic actin in mammalian cells to probe for the presence of actin at the neuromuscular junction. Immunocytochemical studies showed that actin or an actinlike molecule is concentrated at neuromuscular junctions of normal and denervated adult rat muscle fibers. Actin is pres...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Current Biology
دوره 24 شماره
صفحات -
تاریخ انتشار 2014